Venlafaxine extended release (ER) in the treatment of generalised anxiety disorder: twenty-four-week placebo-controlled dose-ranging study
- PMID: 11435263
- DOI: 10.1192/bjp.179.1.15
Venlafaxine extended release (ER) in the treatment of generalised anxiety disorder: twenty-four-week placebo-controlled dose-ranging study
Erratum in
- Br J Psychiatry 2001 Aug;179:181
Abstract
Background: Generalised anxiety disorder (GAD) has received less study than other anxiety disorders, particularly its long-term treatment.
Aims: To assess the efficacy and safety of venlafaxine extended release (ER) in patients with GAD.
Method: A total of 541 out-patients, 18-86 years old, were recruited to this 24-week, placebo-controlled, double-blind study of three fixed doses (37.5, 75 and 150 mg/day) of venlafaxine ER.
Results: All doses of venlafaxine ER showed efficacy superior to placebo, apparent from week 2, that was sustained throughout the 24-week study for the two higher doses. The discontinuation rate did not differ significantly among the treatment groups.
Conclusions: Venlafaxine ER is an effective and safe treatment for GAD for up to 6 months.
Comment in
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Reporting of randomised trials.Br J Psychiatry. 2002 Feb;180:185-6. doi: 10.1192/bjp.180.2.185. Br J Psychiatry. 2002. PMID: 11823333 No abstract available.
