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Review
. 2001 Jun:16:114-8.
doi: 10.1152/physiologyonline.2001.16.3.114.

Molecular physiology of renal p-aminohippurate secretion

G Burckhardt  1 , A Bahn, N A Wolff
Affiliations
Review

Molecular physiology of renal p-aminohippurate secretion

G Burckhardt et al. News Physiol Sci. 2001 Jun.

Abstract

Renal proximal tubules secrete various organic anions, including drugs and p-aminohippurate (PAH). Uptake of PAH from blood into tubule cells occurs by exchange with intracellular alpha-ketoglutarate and is mediated by the organic anion transporter 1. PAH exit into tubule lumen is species specific and may involve ATP-independent and -dependent transporters.

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