Review
doi: 10.1152/physiologyonline.2001.16.3.114.
Molecular physiology of renal p-aminohippurate secretion
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- PMID: 11443229
- DOI: 10.1152/physiologyonline.2001.16.3.114
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Review
Molecular physiology of renal p-aminohippurate secretion
News Physiol Sci.
2001 Jun.
Abstract
Renal proximal tubules secrete various organic anions, including drugs and p-aminohippurate (PAH). Uptake of PAH from blood into tubule cells occurs by exchange with intracellular alpha-ketoglutarate and is mediated by the organic anion transporter 1. PAH exit into tubule lumen is species specific and may involve ATP-independent and -dependent transporters.
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