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. 2001 Jun 26;11(12):R460-2.
doi: 10.1016/s0960-9822(01)00281-0.

Membrane traffic: how do GGAs fit in with the adaptors?

M W Black  1 , H R Pelham
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Free article

Membrane traffic: how do GGAs fit in with the adaptors?

M W Black et al. Curr Biol. .
Free article

Abstract

The AP-1 adaptor complex has been cast as the major player in clathrin coat formation for vesicular transport from the trans-Golgi to the endocytic pathway. But new results on 'GGA' proteins have raised doubts about this paradigm and suggest both a new sorting mechanism and an unexpected complexity in the roles of clathrin.

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