Strain differences during intraventricular infusion of norepinephrine: possible role of receptor sensitivity
- PMID: 1145205
- DOI: 10.1126/science.1145205
Strain differences during intraventricular infusion of norepinephrine: possible role of receptor sensitivity
Abstract
Two rat strains previously shown to differ with respect to behavioral activity, regional brain tyrosine hydroxylase activity, and norepinephrine-elicited accumulation of adenosine 3', 5'-monophosphate exhibited differential behavioral responsiveness during the intraventricular infusion of norepinephrine. The results are interpreted in terms of differential catecholamine receptor sensitivity.
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