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. 1975 Jul 25;189(4199):301-3.
doi: 10.1126/science.1145205.

Strain differences during intraventricular infusion of norepinephrine: possible role of receptor sensitivity

D S Segal, M A Geyer, B E Weiner

Strain differences during intraventricular infusion of norepinephrine: possible role of receptor sensitivity

D S Segal et al. Science. .

Abstract

Two rat strains previously shown to differ with respect to behavioral activity, regional brain tyrosine hydroxylase activity, and norepinephrine-elicited accumulation of adenosine 3', 5'-monophosphate exhibited differential behavioral responsiveness during the intraventricular infusion of norepinephrine. The results are interpreted in terms of differential catecholamine receptor sensitivity.

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