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Comparative Study
. 2001 May-Jun;43(3):119-24.
doi: 10.1590/s0036-46652001000300001.

Genetic relationships among serogroup B: serotype 4 Neisseria meningitidis strains

A P Lemos  1 , C T Sacchi, M V Paiva, T I Yara, C E Melles, L W Mayer
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Free article
Comparative Study

Genetic relationships among serogroup B: serotype 4 Neisseria meningitidis strains

A P Lemos et al. Rev Inst Med Trop Sao Paulo. 2001 May-Jun.
Free article

Abstract

We compared the results obtained by serotyping of PorB epitopes using an expanded panel of monoclonal antibodies (mAb) including mAb 7 and mAb 10, with results obtained by RFLP of rRNA genes (ribotyping). The purpose of this study was to assess the correlation between phenotypic- and genotypic- methods for typing N. meningitidis. The ribotypes obtained using ClaI or EcoRV endonucleases grouped the strains in seven and two different patterns, respectively. This additional characterization of PorB epitopes improved the correlation between these two methods of typing N. meningitidis.

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