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Comment
. 2001 Aug;69(2):461-3.
doi: 10.1086/321968.

The D13S171 marker, misannotated to BRCA2, links the AS3 gene to various cancers

P Geck, C Sonnenschein, A M Soto
Comment

The D13S171 marker, misannotated to BRCA2, links the AS3 gene to various cancers

P Geck et al. Am J Hum Genet. 2001 Aug.
No abstract available

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Figures

Figure 1
Figure 1
Map positions of markers and genes on the nucleotide sequence of the 13q12-13 contig. Boxes indicate markers that have been the main focus of clinical studies. Top, Microsatellite markers. Markers are shown with numbers that indicate the positions of the first nucleotides of the amplicons. The scale refers to that of the 13q12-13 contig. The hatched bar represents the homozygous deletion in a pancreatic adenocarcinoma that partially removed the AS3 coding region. The left border of the deletion is centromeric to DPC2 (at ∼450,000 position), and its right border is telomeric to DPC1 (at ∼780,000–830,000 positions) (Schutte et al. 1995). Middle, the identified coding sequences in the area. Sequences are shown on the same scale as in the top panel. The arrowheads indicate the directions of transcription. The names in parentheses indicate alternative names or alternative transcripts. Bottom, the nucleotide sequence of the 13q12-13 contig in 0.1-Mb units.
See this image and copyright information in PMC

Comment on

References

Electronic-Database Information

    1. Cooperative Human Linkage Center, http://lpg.nci.nih.gov/CHLC/ (for databases of microsatellite markers)
    1. GeneMap99, http://www.ncbi.nlm.nih.gov/genemap99/ (for radiation-hybrid data)
    1. Human Genome Project, http://research.marshfield.org/genetics (for 13q12-q13 contig)
    1. Unified Data Base, http://bioinformatics.weizmann.ac.il/udb/ (for STS data)

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