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Review
. 2001 Aug;13(4):417-21.
doi: 10.1016/s0955-0674(00)00230-1.

The essence of excitation

R J Reimer  1 , R T Fremeau Jr, E E Bellocchio, R H Edwards
Affiliations
Review

The essence of excitation

R J Reimer et al. Curr Opin Cell Biol. 2001 Aug.

Abstract

The amino acid glutamate is the major excitatory neurotransmitter in a range of organisms from Caenorhabditis elegans to mammals, and it mediates the information processing that underlies essentially all behavior. Recent advances in our understanding of glutamate storage and release now illuminate how this ubiquitous amino acid can function as a signalling molecule.

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