Review
doi: 10.1111/j.1749-6632.2001.tb03563.x.
Endocrinological basis of sex differences in cocaine-induced behavioral responses
Affiliations
- PMID: 11458535
- DOI: 10.1111/j.1749-6632.2001.tb03563.x
Item in Clipboard
Review
Endocrinological basis of sex differences in cocaine-induced behavioral responses
Ann N Y Acad Sci.
2001 Jun.
Abstract
Currently, 1.8 million Americans use cocaine, 30% of whom are females. Sex differences in the pattern of cocaine abuse may reside in neuroendocrinological modulations that affect the use of and/or dependence on cocaine. This review discusses sex differences in cocaine-induced behavioral and molecular alterations in the central nervous system, with emphasis on the role of endocrine responses in the neuronal modulations of this drug. Mechanisms and data supporting the role of the hypothalamic-gonadal axis in the modulation of cocaine-induced behavioral and molecular alterations are also provided.
Similar articles
-
Temporal effects of estrogen and progesterone on behavioral and endocrinological responses to acute cocaine administration.Cell Mol Biol (Noisy-le-grand). 2003 Dec;49(8):1269-74. Cell Mol Biol (Noisy-le-grand). 2003. PMID: 14983997
-
Progesterone inhibits behavioral responses and estrogen increases corticosterone levels after acute cocaine administration.Pharmacol Biochem Behav. 2005 Apr;80(4):603-10. doi: 10.1016/j.pbb.2005.01.010. Pharmacol Biochem Behav. 2005. PMID: 15820530
-
Sex, steroids, and stimulant sensitivity.Ann N Y Acad Sci. 2001 Jun;937:188-201. doi: 10.1111/j.1749-6632.2001.tb03565.x. Ann N Y Acad Sci. 2001. PMID: 11458537
-
Regulation of opioid receptors by cocaine.Ann N Y Acad Sci. 2001 Jun;937:74-92. doi: 10.1111/j.1749-6632.2001.tb03559.x. Ann N Y Acad Sci. 2001. PMID: 11458541 Review.
-
Progesterone attenuates cocaine-induced responses.Horm Behav. 2010 Jun;58(1):22-32. doi: 10.1016/j.yhbeh.2009.10.002. Epub 2009 Oct 9. Horm Behav. 2010. PMID: 19819242 Review.
Cited by
-
Repeated maternal separation: differences in cocaine-induced behavioral sensitization in adult male and female mice.Psychopharmacology (Berl). 2005 Mar;178(2-3):202-10. doi: 10.1007/s00213-004-1989-1. Epub 2004 Aug 21. Psychopharmacology (Berl). 2005. PMID: 15322726
-
Prenatal cocaine exposure increases anxiety, impairs cognitive function and increases dendritic spine density in adult rats: influence of sex.Neuroscience. 2010 Sep 1;169(3):1287-95. doi: 10.1016/j.neuroscience.2010.04.067. Epub 2010 May 27. Neuroscience. 2010. PMID: 20553818 Free PMC article.
-
Subchronic nandrolone administration reduces cocaine-induced dopamine and 5-hydroxytryptamine outflow in the rat nucleus accumbens.Psychopharmacology (Berl). 2010 Apr;209(3):271-81. doi: 10.1007/s00213-010-1796-9. Epub 2010 Feb 26. Psychopharmacology (Berl). 2010. PMID: 20186395
-
Cocaine-and-Amphetamine Regulated Transcript (CART) peptide attenuates dopamine- and cocaine-mediated locomotor activity in both male and female rats: lack of sex differences.Neuropeptides. 2014 Apr;48(2):75-81. doi: 10.1016/j.npep.2014.01.002. Epub 2014 Jan 10. Neuropeptides. 2014. PMID: 24630272 Free PMC article.
-
Inactivation of ERK1/2 Signaling in Dopaminergic Neurons by Map Kinase Phosphatase MKP3 Regulates Dopamine Signaling and Motivation for Cocaine.J Neurosci. 2024 Jan 31;44(5):e0727232023. doi: 10.1523/JNEUROSCI.0727-23.2023. J Neurosci. 2024. PMID: 38296649 Free PMC article.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
