Large-scale production of mouse phenotypes: the search for animal models for inherited diseases in humans
- PMID: 11465734
- DOI: 10.1093/bib/2.2.170
Large-scale production of mouse phenotypes: the search for animal models for inherited diseases in humans
Abstract
This paper is aimed principally at bioinformaticians and biologists as an introduction to recent advances in mouse mutagenesis, concentrating on genome-wide screens utilising the powerful mutagen N-ethyl-N-nitroso-urea (ENU). It contains a brief background to the underlying genetics as well as details of the practical aspects of organisation and data capture for such projects.
Comment in
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Gene function. Part 2.Brief Bioinform. 2001 May;2(2):108-10. doi: 10.1093/bib/2.2.108. Brief Bioinform. 2001. PMID: 11465729 No abstract available.
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