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Clinical Trial
. 2001 Aug;22(2):107-13.
doi: 10.1053/ejvs.2001.1413.

Treatment efficacy of intermittent claudication by surgical intervention, supervised physical exercise training compared to no treatment in unselected randomised patients I: one year results of functional and physiological improvements

J Gelin  1 , L Jivegård, C Taft, J Karlsson, M Sullivan, A G Dahllöf, R Sandström, B Arfvidsson, K Lundholm
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Free article
Clinical Trial

Treatment efficacy of intermittent claudication by surgical intervention, supervised physical exercise training compared to no treatment in unselected randomised patients I: one year results of functional and physiological improvements

J Gelin et al. Eur J Vasc Endovasc Surg. 2001 Aug.
Free article

Abstract

Objectives: to compare the effect of surgery, exercise and simple observation on maximum exercise power in claudicants.

Design: prospective, randomised study.

Methods: a total of 264 unselected claudicants were randomised to supervised exercise training, invasive treatment (open surgical or endovascular procedures) or observation. One year treatment outcomes were analysed on an intention to-treat basis.

Results: invasively treated patients showed a significant improvement in maximum walking power, stopping distance, post-ischaemic blood flow and big toe pressure at one year. Patients randomised to physical exercise training or to the control group did not improve in any outcome measure.

Conclusion: invasive treatment increased walking capacity, leg blood pressure and flow. Supervised physical exercise training offered no therapeutic advantage compared to untreated controls.

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