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Review
. 1999 Spring;1(1):57-70.
doi: 10.1089/152091599317585.

Measuring glycated proteins: clinical and methodological aspects

M P Cohen  1 , R S Clements
Affiliations
Review

Measuring glycated proteins: clinical and methodological aspects

M P Cohen et al. Diabetes Technol Ther. 1999 Spring.

Abstract

The recognition that nonenzymatic glycation, wherein free sugar condenses with certain reactive protein amino groups, is increased in hyperglycemic states has led to improved means for assessing diabetic control through the measurement of concentrations of glycated proteins in the circulation. This article reviews the chemistry, methods for measurement, and clinical relevance of circulating glycated proteins in the management of diabetes.

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