Reproductive outcome after laparoscopic instillation of hyperosmolar glucose into unruptured tubal pregnancies

Abstract

Objective: To determine intrauterine and ectopic pregnancy rates after local instillation of 50% glucose into unruptured tubal pregnancies.

Design: Retrospective cohort of 183 patients, who were observed for 16 to 108 months (median, 64 months).

Setting: University hospital.

Patient(s): One hundred eighty-three women who underwent laparoscopic instillation of hyperosmolar glucose for unruptured tubal pregnancies.

Intervention(s): Completion of questionnaires.

Main outcome measure(s): Pregnancy rate, tubal recurrence rate.

Result(s): A total of 124 women returned the questionnaire and had a desire for spontaneous conception. The conception rate and the intrauterine pregnancy rate were 79% and 73%, respectively. Seventy percent of all women with desire for spontaneous conception had live births. The rate of subsequent ectopic pregnancies was 12%. Tubal patency of the treated tube was demonstrated in 69% of 39 women at hysterosalpingography.

Conclusion(s): The long-term prognosis for conception after laparoscopic instillation of hyperosmolar glucose for unruptured tubal pregnancy is favorable and comparable to that of other conservative treatments.