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Case Reports
. 2001 Jul 21;358(9277):207-8.
doi: 10.1016/S0140-6736(01)05410-1.

Linezolid resistance in a clinical isolate of Staphylococcus aureus

S Tsiodras, H S Gold, G Sakoulas, G M Eliopoulos, C Wennersten, L Venkataraman, R C Moellering, M J Ferraro
Case Reports

Linezolid resistance in a clinical isolate of Staphylococcus aureus

S Tsiodras et al. Lancet. .

Abstract

The new oxazolidinone antimicrobial, linezolid, has been approved for the treatment of infections caused by various gram-positive bacteria, including meticillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE). Although instances of linezolid resistance in VRE have been reported, resistance has not been encountered among clinical isolates of S aureus. We have characterised an MRSA isolate resistant to linezolid that was recovered from a patient treated with this agent for dialysis-associated peritonitis.

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