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Clinical Trial
. 1998 Jul;18(7):399-401.

[Clinical study of purified xuefu capsule in treating angina pectoris]

[Article in Chinese]
X Wang  1 , K Chen, W Wang
Affiliations
  • PMID: 11477813
Clinical Trial

[Clinical study of purified xuefu capsule in treating angina pectoris]

[Article in Chinese]
X Wang et al. Zhongguo Zhong Xi Yi Jie He Za Zhi. 1998 Jul.

Abstract

Objective: To study the effect of purified Xuefu Capsule (PXFC) in treating angina pectoris (AP).

Methods: Fifty-seven patients with AP were randomly divided into two groups. Group A (30 cases) was treated with PXFC and western medicine, and group B(27 cases) with western medicine (isosorbide dinitrate, diltiazem or atenolol) alone.

Results: The total effective rates and ECG ST-T changes of AP were 93.3% and 63.3% respectively in group A. These results were all superior to those of group B (P < 0.05). Moreover, in group A the level of plasma endothelin (ET-1) decreased from 85.09 +/- 37.56 ng/L to 61.19 +/- 4.02 ng/L, and that of calcitonin gene related peptide (CGRP) increased from 58.64 +/- 19.30 ng/L to 88.87 +/- 20.41 ng/L. Comparing with group B, these changes were statistically different (P < 0.01).

Conclusions: The effects of adding PXFC on conventional treatment with western medicine were better than those of western medicine.

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