Aerobic lactate production by mammary tissue
- PMID: 1147900
- PMCID: PMC1165297
- DOI: 10.1042/bj1460273
Aerobic lactate production by mammary tissue
Abstract
Glucose uptake and L-lactate production were measured in cell, slice and intact tissue preparations of mammary glands from late-pregnant and lactating rats. The tissues showed extensive conversion of glucose into lactate in vitro, but not in vivo. Therefore aerobic lactate formation is not a normal feature of mammary tissue, but occurs in vitro as the result of some metabolic derangement.
Similar articles
-
Comparison of glucose metabolism in the lactating mammary gland of the rat in vivo and in vitro. Effects of starvation, prolactin or insulin deficiency.Biochem J. 1977 Apr 15;164(1):153-9. doi: 10.1042/bj1640153. Biochem J. 1977. PMID: 141926 Free PMC article.
-
Lipogenesis by acini from mammary gland of lactating rats.J Biol Chem. 1974 Nov 25;249(22):7348-57. J Biol Chem. 1974. PMID: 4373465 No abstract available.
-
The utilization of glucose and production of lactate by in vitro preparations of rat small intestine: effects of vascular perfusion.J Physiol. 1976 Mar;255(3):775-95. doi: 10.1113/jphysiol.1976.sp011307. J Physiol. 1976. PMID: 1263142 Free PMC article.
-
Substrate selection and oxygen uptake by the lactating mammary gland.Proc Nutr Soc. 1995 Mar;54(1):165-75. doi: 10.1079/pns19950046. Proc Nutr Soc. 1995. PMID: 7568251 Review. No abstract available.
-
Metabolic alterations and lactate overproduction in insulin-resistant states.Adv Exp Med Biol. 1994;354:203-10. doi: 10.1007/978-1-4899-0939-8_15. Adv Exp Med Biol. 1994. PMID: 8067287 Review. No abstract available.
Cited by
-
Comparison of glucose metabolism in the lactating mammary gland of the rat in vivo and in vitro. Effects of starvation, prolactin or insulin deficiency.Biochem J. 1977 Apr 15;164(1):153-9. doi: 10.1042/bj1640153. Biochem J. 1977. PMID: 141926 Free PMC article.
-
Interactions of glucose, acetoacetate and insulin in mammary-gland slices of lactating rats.Biochem J. 1975 Aug;150(2):145-52. doi: 10.1042/bj1500145. Biochem J. 1975. PMID: 1180913 Free PMC article.
-
Arteriovenous glucose differences across the mammary gland of the fed, starved, and re-fed lactating rat.Biochem J. 1986 Oct 15;239(2):269-74. doi: 10.1042/bj2390269. Biochem J. 1986. PMID: 3545180 Free PMC article.
-
Milk glucose as an index of the intracellular glucose concentration of rat mammary gland.Biochem J. 1975 Oct;152(1):153-5. doi: 10.1042/bj1520153. Biochem J. 1975. PMID: 1212221 Free PMC article.
-
Monosaccharide transport in the mammary gland of the intact lactating rat.Biochem J. 1984 Feb 15;218(1):213-9. doi: 10.1042/bj2180213. Biochem J. 1984. PMID: 6370237 Free PMC article.
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources