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Review
. 2001 Aug;7(8):899-905.
doi: 10.1038/90935.

Autoimmune disease: why and where it occurs

P Marrack  1 , J Kappler, B L Kotzin
Affiliations
Review

Autoimmune disease: why and where it occurs

P Marrack et al. Nat Med. 2001 Aug.

Abstract

Autoimmune disease is controlled by genetic and environmental factors. Both of these affect susceptibility to autoimmunity at three levels: the overall reactivity of the immune system, the specific antigen and its presentation, and the target issue.

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