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. 1975 Jun;37(6):668-71.
doi: 10.1136/hrt.37.6.668.

Advanced heart block aggravated by carbamazepine

Advanced heart block aggravated by carbamazepine

B Beermann et al. Br Heart J. 1975 Jun.

Abstract

This report presents a serious adverse reaction to the anticonvulsant compound carbamazepine. A woman was admitted to hospital for recurrent attacks of syncope. She suffered from atrioventricular block of the Mobitz type II. Carbamazepine suppressed the conduction in her already defective Purkinje fibres and induced ventricular stand-still with subsequent Adams-Stokes attacks.

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References

    1. J Pharmacol Exp Ther. 1970 Jun;173(2):323-35 - PubMed
    1. Circulation. 1973 Jun;47(6):1234-41 - PubMed

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