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. 2001 Aug 9;3(16):2435-8.
doi: 10.1021/ol015979n.

An expeditious approach toward the total synthesis of CP-263,114

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An expeditious approach toward the total synthesis of CP-263,114

J T Njardarson et al. Org Lett. .

Abstract

[reaction: see text] Assembly of the carbocyclic core of CP-263,114 has been accomplished efficiently and in high yield. Key steps include a phenolic oxidation/intramolecular Diels-Alder sequence, tandem radical cyclization, and the late-stage fragmentation of a densely functionalized isotwistane skeleton.

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