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. 2001 Aug 9;3(16):2539-41.
doi: 10.1021/ol016208m.

3-Aryl-2-oxazolidinones through the palladium-catalyzed N-arylation of 2-oxazolidinones

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3-Aryl-2-oxazolidinones through the palladium-catalyzed N-arylation of 2-oxazolidinones

S Cacchi et al. Org Lett. .

Abstract

[reaction: see text] 3-Aryl-2-oxazolidinones are obtained in good yields through the palladium-catalyzed N-arylation of 2-oxazolidinones with aryl bromides. The nature of aryl bromides, phosphine ligands, bases, and solvents strongly affects the reaction outcome.

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