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Review
. 2001 Aug;2(8):569-77.
doi: 10.1038/35085034.

Mycobacterium tuberculosis: here today, and here tomorrow

D G Russell  1
Affiliations
Review

Mycobacterium tuberculosis: here today, and here tomorrow

D G Russell. Nat Rev Mol Cell Biol. 2001 Aug.

Abstract

Mycobacterium tuberculosis is a highly successful pathogen that parasitizes the macrophages of its host. Its success can be attributed directly to its ability to manipulate the phagosome that it resides in and to prevent the normal maturation of this organelle into an acidic, hydrolytic compartment. As the macrophage is key to clearing the infection, the interplay between the pathogen and its host cell reflects a constant battle for control.

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