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Review
. 2001 Aug;2(8):599-609.
doi: 10.1038/35085068.

Transcriptional regulation by the phosphorylation-dependent factor CREB

B Mayr  1 , M Montminy
Affiliations
Review

Transcriptional regulation by the phosphorylation-dependent factor CREB

B Mayr et al. Nat Rev Mol Cell Biol. 2001 Aug.

Abstract

The transcription factor CREB -- for 'cyclic AMP response element-binding protein' -- functions in glucose homeostasis, growth-factor-dependent cell survival, and has been implicated in learning and memory. CREB is phosphorylated in response to various signals, but how is specificity achieved in these signalling pathways?

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