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. 2001 Aug 10;286(1):150-5.
doi: 10.1006/bbrc.2001.5350.

Automated mode-of-action detection by metabolic profiling

N Aranìbar  1 , B K Singh, G W Stockton, K H Ott
Affiliations

Automated mode-of-action detection by metabolic profiling

N Aranìbar et al. Biochem Biophys Res Commun. .

Abstract

Rapid classification and identification of the mode-of-action of bioactive compounds applied to plants can be achieved by a robust and easy-to-use metabolic-profiling method. This method uses artificial neural network analysis of one-dimensional proton NMR spectra of aqueous plant extracts to rapidly classify changes in the total metabolic profile caused by application of crop protection chemicals.

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