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Case Reports
. 2001 Aug;58(2):281.
doi: 10.1016/s0090-4295(01)01138-4.

A case of familial clustering of interstitial cystitis and chronic pelvic pain syndrome

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Case Reports

A case of familial clustering of interstitial cystitis and chronic pelvic pain syndrome

J D Dimitrakov. Urology. 2001 Aug.

Abstract

A case of familial clustering of interstitial cystitis (IC) and chronic pelvic pain syndrome (CPPS), a symptom complex similar to IC that occurs in men, is reported. The proband was a 28-year-old woman with a 6-month history of severe frequency, urgency, and genital pain. After cystoscopy with hydrodistention and biopsy, a diagnosis of IC was made. IC was also diagnosed in the patient's mother and in two of her brothers, previously considered to have CPPS (category IIIB CPPS). A third brother was asymptomatic. This case highlights the importance of genetic factors in the onset of symptoms and natural history of IC and CPPS.

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