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. 2001 Aug;6(8):354-8.
doi: 10.1016/s1360-1385(01)01960-4.

The U-box protein family in plants

C Azevedo  1 , M J Santos-Rosa, K Shirasu
Affiliations

The U-box protein family in plants

C Azevedo et al. Trends Plant Sci. 2001 Aug.

Abstract

The U-box is a highly conserved domain recently identified at the C terminus of yeast UFD2, an E4 ubiquitination factor. In yeast, UFD2 is the only U-box-containing protein, but there are two UFD2 homologs and several other proteins containing a U-box domain in humans. Intriguingly, a database search revealed 37 predicted proteins containing a U-box in Arabidopsis. The plant U-box (PUB) proteins form five distinct subclasses, suggesting that they play diverse roles. The ARC1 gene from Brassica, required for self-incompatibility, is currently the only PUB gene functionally characterized. Here, we discuss the characteristics and possible functions of the PUB gene family.

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