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. 1975 Jun-Jul;32(02):383-6.
doi: 10.1016/0014-2999(75)90310-6.

Apomorphine as a discriminative stimulus, and its antagonism by haloperidol

F C Colpaert, C J Niemegeers, J J Kuyps, P A Janssen

Apomorphine as a discriminative stimulus, and its antagonism by haloperidol

F C Colpaert et al. Eur J Pharmacol. 1975 Jun-Jul.

Abstract

At a non-stereotypogenic dose (0.16 mg/kg, s.c.), apomorphine was shown to produce a discriminative stimulus in rats. The apomorphine-produced stimulus was found to be effectively antagonized by haloperidol. It is suggested that apomorphine's ability to stimulate central dopamine receptors is directly related to its cueing action.

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