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Clinical Trial
. 2001 Jul;18(7):387-90.
doi: 10.1023/a:1016674523317.

Influence of midluteal serum prolactin on outcome of pregnancy after IVF-ET: a preliminary study

T Ozaki  1 , K Takahashi, H Kurioka, K Miyazaki
Affiliations
Clinical Trial

Influence of midluteal serum prolactin on outcome of pregnancy after IVF-ET: a preliminary study

T Ozaki et al. J Assist Reprod Genet. 2001 Jul.

Abstract

Purpose: To investigate the relationship between serum prolactin levels in the midluteal phase and the prognosis of pregnancy after IVF-ET.

Design: Prospective study;

Setting: Shimane Medical University Hospital;

Patients: 29 patients completing their 34th IVF cycle; and

Main outcome measures: Serum levels of prolactin, estradiol-17 beta, and progesterone in the midluteal phase.

Results: Midluteal prolactin levels were significantly lower in patients with early pregnancy loss than in the successful pregnancy group. The mean progesterone/prolactin ratio and the estradiol-17 beta/prolactin ratio were highest in patients with early pregnancy loss and were lowest in patients with successful pregnancies.

Conclusions: Findings of this study suggest that measurement of the serum prolactin concentration in the midluteal phase is useful for predicting the outcome of IVF-ET.

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References

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