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. 1975 Jun;11(3):221-4.
doi: 10.1007/BF00422325.

Increased kidney size and glomerular filtration rate in untreated juvenile diabetes: normalization by insulin-treatment

C E Mogensen, M J Andersen

Increased kidney size and glomerular filtration rate in untreated juvenile diabetes: normalization by insulin-treatment

C E Mogensen et al. Diabetologia. 1975 Jun.

Abstract

Glomerular filtration rate (GFR), renal plasma flow (RPF) and roentigenographic kiendy size were measured in six newly diagnosed male diabetics with a mean age of 25 years. Glomerular filtration rate was elevated before treatment to the same extent as found previously. A significant fall in both kidney size and glomerular filtration rate was found after treatment with insulin for 3 months. These results support further the concept that there is a basal connection between enlarged kidneys and the elevated GFR of early diabetes.

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