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. 2001 Sep;45(9):2524-8.
doi: 10.1128/AAC.45.9.2524-2528.2001.

In vitro activities of 10 antifungal drugs against 508 dermatophyte strains

B Fernández-Torres  1 , A J Carrillo, E Martín, A Del Palacio, M K Moore, A Valverde, M Serrano, J Guarro
Affiliations

In vitro activities of 10 antifungal drugs against 508 dermatophyte strains

B Fernández-Torres et al. Antimicrob Agents Chemother. 2001 Sep.

Abstract

We have tested 508 strains belonging to 24 species of dermatophytes against 10 antifungal drugs following mainly the NCCLS (M38-P) standard for filamentous fungi. However, several important factors, such as the temperature (28 versus 35 degrees C) and time of incubation (4 to 10 days versus 21 to 74 h), have been modified. The antifungals used were itraconazole, ketoconazole, miconazole, clotrimazole, voriconazole, terbinafine, amphotericin B, fluconazole, UR-9825, and G-1. In general, with the exception of fluconazole and G-1, all antifungals were shown to be highly effective.

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References

    1. Berger A R. Common superficial fungal infections in patient with AIDS. Clin Infect Dis. 1996;22:128–132. - PubMed
    1. Butty P, Lebecq J C, Mallié M, Bastide J M. Evaluation of the susceptibility of dermatophytes to antifungal drugs: a new technique. J Med Vet Mycol. 1995;33:403–409. - PubMed
    1. Fernández-Torres B, Vázquez-Veiga H, Llovo X, Pereiro M, Jr, Guarro J. In vitro susceptibility to itraconazole, clotrimazole, ketoconazole and terbinafine of 100 isolates of Trichophyton rubrum. Chemotherapy. 2000;46:390–394. - PubMed
    1. Gehrt A, Peter J, Pizzo P A, Walsh T J. Effect of increasing inoculum sizes of pathogenic filamentous fungi on MICs of antifungal agents by broth microdilution method J. Clin Microbiol. 1995;33:1302–1307. - PMC - PubMed
    1. Hazen K C. Fungicidal versus fungistatic activity of terbinafine and itraconazole: an in vitro comparison. J Am Acad Dermatol. 1998;38:S37–S41. - PubMed

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