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. 2001 Sep;45(9):2635-7.
doi: 10.1128/AAC.45.9.2635-2637.2001.

In vitro antifungal activities of the new triazole UR-9825 against clinically important filamentous fungi

J Capilla  1 , M Ortoneda, F J Pastor, J Guarro
Affiliations

In vitro antifungal activities of the new triazole UR-9825 against clinically important filamentous fungi

J Capilla et al. Antimicrob Agents Chemother. 2001 Sep.

Abstract

We used a modified reference microdilution method (the M-38P method) to evaluate the in vitro activities of the new triazole UR-9825 in comparison with those of amphotericin B against 77 strains of opportunistic filamentous fungi. UR-9825 was clearly more active than amphotericin B against all fungi except Fusarium solani and Scytalidium spp. Notably, UR-9825 had low MICs for Aspergillus fumigatus and Paecilomyces lilacinus (MICs at which 90% of isolates are inhibited, 0.125 microg/ml for both species).

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