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Comparative Study
. 1975 Jul 23;28(3):263-7.
doi: 10.1007/BF00278556.

Toxicity of antibiotics on cultured human skin fibroblasts

W Byarugaba, H W Rüdiger, T Koske-Westphal, W Wöhler, E Passarge
Comparative Study

Toxicity of antibiotics on cultured human skin fibroblasts

W Byarugaba et al. Humangenetik. .

Abstract

Human diploid fibroblasts cultured in Dulbecco's Modified Eagle's medium (DME) were exposed to different concentrations of 15 antibiotics to determine the limiting toxic concentration. The number of cells surviving after antibiotic treatment was given as the index of toxicity. No visible chromosomal damage could be detected when half the maximal toxic concentration was applied. The maximum limiting concentration was found to be the same for both the preconfluent and postconfluent phases.

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References

    1. Br Med J. 1952 Nov 15;2(4793):1070-2 - PubMed
    1. J Invest Dermatol. 1953 May;20(5):357-72 - PubMed

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