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. 1975 Jan;11(1):76-80.

Calculation of drug dosage regimens in patients with renal disease: a new nomographic method

  • PMID: 1150365

Calculation of drug dosage regimens in patients with renal disease: a new nomographic method

P Spring. Int J Clin Pharmacol Biopharm. 1975 Jan.

Abstract

A simple nomograph is described which allows to estimate graphically the individual elimination rate constants of 43 drugs in patients with renal disease based on the endogenous creatinine clearance or the serum creatinine concentration. It is shown how modified dosage regimens are calculated from the estimated elimination rate constants.

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