Review
doi: 10.1080/20014091111875.
Cell migration/chemotaxis: biphasic dose responses
Affiliations
- PMID: 11504186
- DOI: 10.1080/20014091111875
Item in Clipboard
Review
Cell migration/chemotaxis: biphasic dose responses
Crit Rev Toxicol.
2001 Jul.
Abstract
The dose-dependent effects of chemoattractants on target cell migration such as tumor cells, fibroblasts, and especially neutrophils were assessed. In general, the dose-response characteristics were strikingly biphasic in nature and were independent of both the target tissue and chemoattractant agent. The assessment included evaluations of the quantitative features of the dose-response relationship, mechanistic foundations of the biphasic responsiveness and clinical applications.
Comment in
-
A critique of "the scientific foundations of hormesis".Crit Rev Toxicol. 2001 Jul;31(4-5):625-9. doi: 10.1080/20014091111884. Crit Rev Toxicol. 2001. PMID: 11504187 No abstract available.
Similar articles
-
Biphasic effects of interleukin-1 alpha on dermal fibroblasts: enhancement of chemotactic responsiveness at low concentrations and of mRNA expression for collagenase at high concentrations.J Invest Dermatol. 1993 Jun;100(6):780-4. doi: 10.1111/1523-1747.ep12476479. J Invest Dermatol. 1993. PMID: 8496618
-
Nerve growth factor stimulates fibronectin-induced fibroblast migration.J Lab Clin Med. 2002 Nov;140(5):329-35. doi: 10.1067/mlc.2002.128347. J Lab Clin Med. 2002. PMID: 12434134
-
The effects of nicotine on vascular smooth muscle cell chemotaxis induced by thrombospondin-1 and fibronectin.Am J Surg. 2011 Nov;202(5):545-8. doi: 10.1016/j.amjsurg.2011.06.016. Epub 2011 Sep 23. Am J Surg. 2011. PMID: 21944292
-
Prostaglandins: biphasic dose responses.Crit Rev Toxicol. 2001 Jul;31(4-5):475-87. doi: 10.1080/20014091111767. Crit Rev Toxicol. 2001. PMID: 11504175 Review.
-
Nitric oxide: biphasic dose responses.Crit Rev Toxicol. 2001 Jul;31(4-5):489-501. doi: 10.1080/20014091111776. Crit Rev Toxicol. 2001. PMID: 11504176 Review.
Cited by
-
Structure-function guided modeling of chemokine-GPCR specificity for the chemokine XCL1 and its receptor XCR1.Sci Signal. 2019 Sep 3;12(597):eaat4128. doi: 10.1126/scisignal.aat4128. Sci Signal. 2019. PMID: 31481523 Free PMC article.
-
Structural and agonist properties of XCL2, the other member of the C-chemokine subfamily.Cytokine. 2015 Feb;71(2):302-11. doi: 10.1016/j.cyto.2014.11.010. Epub 2014 Dec 11. Cytokine. 2015. PMID: 25497737 Free PMC article.
-
An investigation of spatial signal transduction in cellular networks.BMC Syst Biol. 2012 Jul 5;6:83. doi: 10.1186/1752-0509-6-83. BMC Syst Biol. 2012. PMID: 22765014 Free PMC article.
-
Theoretical and experimental models of hormetic fusion tubulogenesis.Dose Response. 2012 Jul 24;11(2):178-90. doi: 10.2203/dose-response.12-004.Fosslien. Print 2013. Dose Response. 2012. PMID: 23930100 Free PMC article.
-
Evaluation of two distinct placental-derived membranes and their effect on tenocyte responses in vitro.J Tissue Eng Regen Med. 2019 Aug;13(8):1316-1330. doi: 10.1002/term.2876. Epub 2019 Jun 13. J Tissue Eng Regen Med. 2019. PMID: 31062484 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
