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. 2001 Jul;40(7):594-7.
doi: 10.2169/internalmedicine.40.594.

Elevated serum myosin light chain I in influenza patients

M Kaji  1 , H Kuno, T Turu, Y Sato, K Oizumi
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Free article

Elevated serum myosin light chain I in influenza patients

M Kaji et al. Intern Med. 2001 Jul.
Free article

Erratum in

Abstract

Objective: Myocarditis has been described as a complication of influenza. Patients with influenza may have symptoms and abnormal laboratory data (including chest X-ray, electrocardiogram, etc.) suggestive of myocarditis, although few observations have been made regarding the prevalence of asymptomatic myocardial injury. We investigated whether influenza can produce myocardial injury without cardiac symptoms.

Methods: During the epidemic of influenza A (H3N2) from 1998 to 1999 in Japan, we examined possible cardiac muscle damage associated with influenza in patients without apparent clinical myocardial injury by measuring serum myosin light chain concentrations.

Patients: Ninety-six influenza-positive patients (46 males and 50 females, average age 43.4 years) without impaired renal function were studied.

Results: Of these patients, 11 (11.4%) had elevated serum myosin light chain I concentrations.

Conclusion: Asymptomatic myocardial injury may be present in patients with influenza even when they have no symptoms suggestive of myocardial injury.

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