Bone metastases from secondary glioblastoma multiforme: a case report
- PMID: 11508813
- DOI: 10.1023/a:1010629618859
Bone metastases from secondary glioblastoma multiforme: a case report
Abstract
Extraneural metastases of glioblastoma multiforme (GBM) are a relatively rare occurrence which usually manifest after de novo GBM. We report a case of a patient with an oligodendroastrocytoma who developed over a period of 12 years malignant progression to glioblastoma followed by multiple cytologically confirmed bone metastases. No 1p deletions were detected in the original tumour. GBM cells disclosed the EGFr(+) and p53(-) immunophenotype more characteristic of a primary GBM.
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