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Case Reports
. 2001 Apr;52(2):141-8.
doi: 10.1023/a:1010629618859.

Bone metastases from secondary glioblastoma multiforme: a case report

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Case Reports

Bone metastases from secondary glioblastoma multiforme: a case report

A Cervio et al. J Neurooncol. 2001 Apr.

Abstract

Extraneural metastases of glioblastoma multiforme (GBM) are a relatively rare occurrence which usually manifest after de novo GBM. We report a case of a patient with an oligodendroastrocytoma who developed over a period of 12 years malignant progression to glioblastoma followed by multiple cytologically confirmed bone metastases. No 1p deletions were detected in the original tumour. GBM cells disclosed the EGFr(+) and p53(-) immunophenotype more characteristic of a primary GBM.

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