doi: 10.1007/s004020100272.
The contribution of vitamin C to healing of experimental fractures
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- PMID: 11510911
- DOI: 10.1007/s004020100272
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The contribution of vitamin C to healing of experimental fractures
Arch Orthop Trauma Surg.
2001 Jul.
Abstract
The benefits of various minerals and vitamins on fracture healing have been demonstrated in animal models. Vitamin C is an essential substance in fracture healing but has not been studied previously on an experimental basis. Sixteen rats were grouped randomly into control and vitamin C-supplemented groups. The right tibias of all rats were fractured by digital manipulation. One group received single high dose of vitamin C intramuscularly. On the 5th, 10th, 15th, and 20th days, two rats from each group were killed and the tibias examined under light microscopy. It was seen that the vitamin C-supplemented group went through the stages of fracture healing faster compared with the control group.
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