doi: 10.1021/jm00239a014.
Carbon-13 magnetic resonance spectroscopy of drugs. Sulfonamides
- PMID: 1151960
- DOI: 10.1021/jm00239a014
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Carbon-13 magnetic resonance spectroscopy of drugs. Sulfonamides
J Med Chem.
1975 May.
Abstract
The natural abundance 13C magnetic resonance spectra of a series of sulfonamide drugs(sulfanilamide, sulfaguanidine,sulfathiazole, sulfasuxidine, sulfadiazine, sulfamerazine, sulfamethiazine, and sulfapyridine) have been determined at 25.15 MHz employing the pulse Fourier transform technique. The chemical shefts have been assigned with the aid of off-resonance and selective proton decoupling techniques, as well as by long-range carbon-13 proton coupling patterns.
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