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. 1975 May;18(5):519-23.

Biotransformation of phenprocoumon in the rat

L R Pohl, R E Haddock, W F Trager
  • PMID: 1151963

Biotransformation of phenprocoumon in the rat

L R Pohl et al. J Med Chem. 1975 May.

Abstract

The metabolic fate of phenprocoumon [3-(alpha-ethylbenzyl)-4-hydroxycoumarin] in the rat is described. The major metabolites, 4',-6-,7-, and 8-hyproxyphenprocoumon, have been identified yb mass spectrometry, TLC, and uv and compared with authentic smaples. Metabolites are mainly excreted via the feces. The results are compared with those previously reported for warfarin.

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