Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1975 Jul;18(7):755-60.
doi: 10.1021/jm00241a023.

Ellipticine derivatives

R W Guthrie, A Brossi, F A Mennona, J G Mullin, R W Kierstead, E Grunberg

Ellipticine derivatives

R W Guthrie et al. J Med Chem. 1975 Jul.

Abstract

Several acyloxy and alkyl derivatives of ellipticine have been prepared. In addition, a modified synthesis leading to the hitherto unobtainable 8,9-dimethoxy- and 8,9-methylenedioxyellipticines is described. Some of the derivatives described herein exhibit antitumor activity. However, none of the compounds showed activity superior to that of the naturally occurring pyridocarbazoles, ellipticine and 9-methoxyellipticine.

PubMed Disclaimer

LinkOut - more resources