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. 1975 Jun;113(6):803-5.
doi: 10.1016/s0022-5347(17)59583-x.

Effects of levodopa on the bladder outlet

M I Murdock, C A Olsson, D S Sax, R J Krane

Effects of levodopa on the bladder outlet

M I Murdock et al. J Urol. 1975 Jun.

Abstract

Lower urinary tract function was studied in patients with Parkinson's disease. A significant proportion of patients receiving levodopa manifested clinical and radiological evidence of bladder outlet obstruction. We believe that neuropharmacologic bladder neck obstruction may be caused by the alpha-adrenergic properties of the metabolites of levodopa.

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