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. 1998;39(4):266-271.
doi: 10.1093/ilar.39.4.266.

Risks of Infection among Laboratory Rats and Mice at Major Biomedical Research Institutions

Robert O. Jacoby  1 , J. Russell Lindsey
Affiliations

Risks of Infection among Laboratory Rats and Mice at Major Biomedical Research Institutions

Robert O. Jacoby et al. ILAR J. 1998.
No abstract available

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Figures

Figure 1
Figure 1
Diagnostic testing of laboratory rats and mice: frequency of use and prevalence of users. Data represent 72 survey respondents.
Figure 2
Figure 2
Sources of cost recovery for diagnostic testing of laboratory rats and mice. Data represent 72 survey respondents.
Figure 3
Figure 3
Staffing for diagnostic laboratories that test rats and mice, expressed as full-time equivalents (FTEs). Data represent 72 survey respondents.
Figure 4
Figure 4
Prevalence of diagnostic procedures available among respondent institutions using laboratory rats and mice. Prevalence is the percentage of 72 respondent institutions in which corresponding conditions were present.
Figure 5
Figure 5
Prevalence of infectious agents in specific pathogen-free mice. Prevalence is the percentage of 72 respondent institutions in which corresponding conditions were present. MCMV, mouse cytomegalovirus; MHV, mouse hepatitis virus; Parvo, minute virus of mice+mouse parvovirus; PVM, pneumonia virus of mice; TMEV, Theiler's murine encephalomyelitis virus. The prevalence of cilia-associated respiratory bacillus, lactic dehydrogenase-elevating virus, lymphocytic choriomeningitis virus, and Sendai virus infections among institutional SPF colonies was 0%.
Figure 6
Figure 6
Prevalence of infectious agents in non-specific pathogen-free mice. Data represent 72 survey respondents. CAR, cilia-associated respiratory; LCM, lymphocytic choriomeningitis virus; LDH-E, lactic dehydrogenase-elevating virus; MHV, mouse hepatitis virus; PVM, pneumonia virus of mice; TMEV, Theiler's murine encephalomyelitis virus. The prevalence of mouse cytomegalovirus and ectromelia virus infections was 0%.
Figure 7
Figure 7
Prevalence of infectious agents in non-specific pathogen-free rats. Data represent 72 survey respondents. CAR, cilia-associated respiratory; PVM, pneumonia virus of mice; TMEV, Theiler's murine encephalomyelitis virus.
Figure 8
Figure 8
Prevalence of infectious agents in specific pathogen-free rats. Data represent 72 survey respondents. Corona includes sialodacryrodacryoadenitis virus and rat coronavirus; Parvo includes rat virus, H-1 virus, and rat parvovirus. CAR, cilia-associated respiratory; PVM, pneumonia virus of mice; TMEV, Theiler's murine encephalomyelitis virus. The prevalence of mycoplasmosis was 0%.
Figure 9
Figure 9
Prevalence of risk because 1 or more agents are “on campus” in specific pathogen-free (SPF) or non-SPF mice. Data represent 72 survey respondents. CAR, cilia-associated respiratory; LCM, lymphocytic choriomeningitis virus; LDH-E, lactic dehydrogenase- elevating virus; MCMV, mouse cytomegalovirus; MTV, mouse thymic virus; PVM, pneumonia virus of mice; TMEV, Theiler's murine encephalomyelitis virus.
Figure 10
Figure 10
Prevalence of risk because 1 or more agents are “on campus” in specific pathogen-free (SPF) or non-SPF rats. Data represent 72 survey respondents. CAR, cilia-associated respiratory; PVM, pneumonia virus of mice; TMEV, Theiler's murine encephalomyelitis virus.
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References

    1. Bhatt PN, Jacoby RO, Morse HC, New AE.editors. Viral and mycoplasmal infections of laboratory rodents: Effects on biomedical research. 1986. Orlando FL: Academic Press.
    1. Casebolt DB, Lindsey JR, Cassell GH. Prevalence rates of infectious agents among commercial breeding populations of rats and mice. Lab Anim Sci 1988. 38:327-329. - PubMed
    1. Compton SR, Barthold SW, Smith AL. The cellular and molecular pathogenesis of coronaviruses.Lab Anim Sci 199343:15-28 - PubMed
    1. Fox JG, Lee A. The role of Helicobacter species in newly recognized gastrointestinal tract diseases of animals.Lab Anim Sci 199747:222-255 - PubMed
    1. Jacoby RO, Ball-Goodrich LJ, Besselsen DG, McKisic MD, Riley LK, Smith AL. 1996. Rodent parvovirus infections. Lab Anim Sci 46:370-380. - PubMed