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Review
. 2001 Oct;11(5):520-6.
doi: 10.1016/s0959-437x(00)00227-6.

Lymphocyte development from hematopoietic stem cells

M Kondo  1 , D C Scherer, A G King, M G Manz, I L Weissman
Affiliations
Review

Lymphocyte development from hematopoietic stem cells

M Kondo et al. Curr Opin Genet Dev. 2001 Oct.

Abstract

The recent application of new techniques, such as multi-color cell sorting and the production of transgenic and gene-knockout mice, has contributed to a better understanding of lymphocyte development from hematopoietic stem cells. Now that we can purify progenitors at different maturational stages during lymphocyte development, the challenge is to understand the processes that govern each developmental stage transition.

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