doi: 10.1007/BF01808151.
Model of early self-replication based on covalent complementarity for a copolymer of glycerate-3-phosphate and glycerol-3-phosphate
Collaborators,
Affiliations
- PMID: 11538679
- DOI: 10.1007/BF01808151
Item in Clipboard
Model of early self-replication based on covalent complementarity for a copolymer of glycerate-3-phosphate and glycerol-3-phosphate
Orig Life Evol Biosph.
1989.
Abstract
Glyceraldehyde-3-phosphate acts as the substrate in a model of early self-replication of a phosphodiester copolymer of glycerate-3-phosphate and glycerol-3-phosphate. This model of self-replication is based on covalent complementarity in which information transfer is mediated by a single covalent bond, in contrast to multiple weak interactions that establish complementarity in nucleic acid replication. This replication model is connected to contemporary biochemistry through its use of glyceraldehyde-3-phosphate, a central metabolite of glycolysis and photosynthesis.
Similar articles
-
Thermal synthesis and hydrolysis of polyglyceric acid.Orig Life Evol Biosph. 1989;19(1):7-19. doi: 10.1007/BF01808284. Orig Life Evol Biosph. 1989. PMID: 11536612
-
The triose model: glyceraldehyde as a source of energy and monomers for prebiotic condensation reactions.Orig Life Evol Biosph. 1987;17(2):107-19. doi: 10.1007/BF01808239. Orig Life Evol Biosph. 1987. PMID: 3627761
-
Phosphorylation of glyceric acid in aqueous solution using trimetaphosphate.Orig Life Evol Biosph. 1996 Feb;26(1):7-13. doi: 10.1007/BF01808156. Orig Life Evol Biosph. 1996. PMID: 11536746
-
Urey Prize Lecture: Planetary Evolution and the Origin of Life.Icarus. 1991;91:93-100. doi: 10.1016/0019-1035(91)90128-g. Icarus. 1991. PMID: 11538106 Review.
-
Three stages in the evolution of the genetic code.Biosystems. 1993;29(2-3):133-41. doi: 10.1016/0303-2647(93)90089-u. Biosystems. 1993. PMID: 8374065 Review.
Cited by
-
The first living systems: a bioenergetic perspective.Microbiol Mol Biol Rev. 1997 Jun;61(2):239-61. doi: 10.1128/mmbr.61.2.239-261.1997. Microbiol Mol Biol Rev. 1997. PMID: 9184012 Free PMC article. Review.
-
The origins of the RNA world.Cold Spring Harb Perspect Biol. 2012 May 1;4(5):a003608. doi: 10.1101/cshperspect.a003608. Cold Spring Harb Perspect Biol. 2012. PMID: 20739415 Free PMC article. Review.
-
Nucleic acid duplexes incorporating a dissociable covalent base pair.Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14837-42. doi: 10.1073/pnas.96.26.14837. Proc Natl Acad Sci U S A. 1999. PMID: 10611299 Free PMC article.