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. 1989:19:179-86.
doi: 10.1007/BF01808151.

Model of early self-replication based on covalent complementarity for a copolymer of glycerate-3-phosphate and glycerol-3-phosphate

A L Weber  1
Collaborators, Affiliations

Model of early self-replication based on covalent complementarity for a copolymer of glycerate-3-phosphate and glycerol-3-phosphate

A L Weber. Orig Life Evol Biosph. 1989.

Abstract

Glyceraldehyde-3-phosphate acts as the substrate in a model of early self-replication of a phosphodiester copolymer of glycerate-3-phosphate and glycerol-3-phosphate. This model of self-replication is based on covalent complementarity in which information transfer is mediated by a single covalent bond, in contrast to multiple weak interactions that establish complementarity in nucleic acid replication. This replication model is connected to contemporary biochemistry through its use of glyceraldehyde-3-phosphate, a central metabolite of glycolysis and photosynthesis.

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References

    1. J Mol Biol. 1972 Nov 28;71(3):735-56 - PubMed
    1. Science. 1985 May 3;228:585-7 - PubMed
    1. Orig Life Evol Biosph. 1987;17(2):107-19 - PubMed
    1. Proc Natl Acad Sci U S A. 1987 Jul;84(13):4398-402 - PubMed
    1. J Mol Evol. 1984;20(2):157-66 - PubMed

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