Inhibitory effect of nickel and chromium upon antibody response of rats to immunization with T-1 phage
- PMID: 1153878
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Inhibitory effect of nickel and chromium upon antibody response of rats to immunization with T-1 phage
Res Commun Chem Pathol Pharmacol.
1975 Jun.
Abstract
Nickel and chromium significantly depressed the circulating antibody response of rats immunized with a viral antigen (T-1 phage). Consistent suppression of antibody was observed in all metal-treated animals; the greatest decrease in antibody titers was noted in animals receiving metals two weeks prior to the initial antigen dose.
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