Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1996 May 1;52(Pt 3):465-8.
doi: 10.1107/s0907444995013564.

A highly efficient 24-condition matrix for the crystallization of nucleic acid fragments

I Berger  1 , C H Kang, N Sinha, M Wolters, A Rich
Affiliations

A highly efficient 24-condition matrix for the crystallization of nucleic acid fragments

I Berger et al. Acta Crystallogr D Biol Crystallogr. .

Abstract

A matrix screen is presented with optimized conditions for the crystallization of nucleic acid fragments. The screen consists of 24 conditions only and utilizes minimal amounts of sample. It has been tested on a series of DNA and RNA oligomers, and yielded diffraction-quality crystals of many specimens including drug-DNA complexes. Preliminary X-ray analysis of the crystals is reported.

PubMed Disclaimer

Publication types

LinkOut - more resources