Comparative Study
doi: 10.1021/ja963563c.
Enantiomeric cross-inhibition in the synthesis of oligonucleotides on a nonchiral template
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- PMID: 11539924
- DOI: 10.1021/ja963563c
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Comparative Study
Enantiomeric cross-inhibition in the synthesis of oligonucleotides on a nonchiral template
J Am Chem Soc.
.
Abstract
NASA: Peptide nucleic acids (PNA) are used as a model for a precursor of RNA in experiments that examine enantiomeric cross-inhibition. Experiments were conducted to facilitate comparison with prior research. Results indicate that enantiomeric cross-inhibition is as problematic in the polymerization of nucleotides on PNA as in RNA and DNA templates.
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