Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1997 Feb 12;119(6):1494-5.
doi: 10.1021/ja963563c.

Enantiomeric cross-inhibition in the synthesis of oligonucleotides on a nonchiral template

J G Schmidt  1 , P E Nielsen, L E Orgel
Collaborators, Affiliations
Comparative Study

Enantiomeric cross-inhibition in the synthesis of oligonucleotides on a nonchiral template

J G Schmidt et al. J Am Chem Soc. .

Abstract

NASA: Peptide nucleic acids (PNA) are used as a model for a precursor of RNA in experiments that examine enantiomeric cross-inhibition. Experiments were conducted to facilitate comparison with prior research. Results indicate that enantiomeric cross-inhibition is as problematic in the polymerization of nucleotides on PNA as in RNA and DNA templates.

PubMed Disclaimer

Publication types

LinkOut - more resources