doi: 10.1016/s0367-326x(01)00281-7.
A novel cytotoxic flavonoid glycoside from Physalis angulata
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- PMID: 11543968
- DOI: 10.1016/s0367-326x(01)00281-7
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A novel cytotoxic flavonoid glycoside from Physalis angulata
Fitoterapia.
2001 Aug.
Abstract
A new flavonol glycoside, myricetin 3-O-neohesperidoside (1) was isolated from a cytotoxic MeOH extract of the leaves of Physalis angulata. Compound 1 showed remarkable cytotoxicity in vitro against murine leukemia cell line P-388, epidermoid carcinoma of the nasopharynx KB-16 cells, and lung adenocarcinoma A-549 with ED(50) values of 0.048, 0.50 and 0.55 microg ml(-1), respectively.
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