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. 2001 Jan-Feb;64(1):38-41.

[Ligands of opioid and sigma receptors and correction of cardiac electrical instability in post-infarction cardiosclerosis]

[Article in Russian]
L N Maslov  1 , Iu B Lishmanov, N V Naryzhnaia, A V Krylatov, S V Tam
Affiliations
  • PMID: 11544802

[Ligands of opioid and sigma receptors and correction of cardiac electrical instability in post-infarction cardiosclerosis]

[Article in Russian]
L N Maslov et al. Eksp Klin Farmakol. 2001 Jan-Feb.

Abstract

Peripheral administration of the mu- or kappa-receptor agonists or sigma-receptor antagonists produced a significant receptor-dependent increase in the ventricular fibrillation threshold in rats with postinfarction cardiosclerosis. The effect was not observed upon administration of the epsilon-receptor agonist beta-endorphin. The receptor and molecular mechanisms of the observed effects are discussed.

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